Heart disease is one of the most terrible illnesses that someone can experience. It is a common disease which affects a large number of people. As reported by World Health Organisation, there are about 17 million people dying each year because of heart-related diseases and this number is 31% of the all overall yearly deaths worldwide. Reasons for heart diseases are numerous but in this article, we are going to focus on the impact of high-fat food consumption in relation to cardiovascular disease.
“A single high-fat meal provokes pathological erythrocyte remodeling and increases myeloperoxidase levels: implications for acute coronary syndrome” is a study published in the Nature Journal, Laboratory Investigation.
Study’s participants were ten healthy men. They had an acceptable medical history and were also physically active as well as acceptable cholesterol levels. Researchers analyzed the risk of the CVD each week and told participants not to consume anything during the night. Vitamin supplement shouldn’t be taken for less than 72 hours before each examination. Also, participants shouldn’t perform hard physical exercises and shouldn’t consume caffeine for less than 24 hours from examination. Half of the participants were given milkshakes with 1000 calories and 80 gram of fat. Cereal meal included also 100 calories but very limited fat and further, each of the participants was given an equal amount of fat according to their body weight.
It is important highlighting that four hours after drinking the milkshake, participants appeared to have an immune response which is very much alike to the response exasperated by infections. On the other hand, participants who drank a milkshake with the same amount of calories but with no fat didn’t show the above-mentioned reaction. This change is obviously momentary but the risk has the tendency to increase if someone continues eating high-fat foods.
Red blood cells were also affected by the single high-fat meal. Their main function is the transportation of oxygen all over our body. After a high-fat meal, these cells not only become smaller but they also create spires and then they emit contamination. A type of white cell called monocyte also changed. These cells usually move throughout blood, in search for old or sickly red blood cells in order to eliminate them but after a high-fat meal, monocytes become fatty when they try to get rid of overdone fat.
Furthermore, researchers were able to discover the presence of myeloperoxidase enzyme (MPO). This enzyme is expressed by white blood cells and is related to heart attack, stress and hard blood cells when it is found in high concentrations. In addition, myeloperoxidase also influences the structure of the chubby red cells by making them less pliable.
This study is a very specific one as it has only observed the effects of a high-fat meal generally on CVD markers and it only did analyses just four hours after the meal. Nevertheless, researchers still mostly support the idea of further and deeper research about the effects of red blood cells changes in heart-related diseases.